Human chimp increase in segmental duplications
QT:” Our results suggest that the evolutionary properties of copy-number mutation differ significantly from other forms of genetic mutation and, in contrast to the hominid slowdown of single-base-pair...
View ArticleWhole-genome reconstruction and mutational signatures in gastric cancer –...
Genome Biol. 2012 Dec 13;13(12):R115. Whole-genome reconstruction and mutational signatures in gastric cancer. Nagarajan N, Bertrand D, Hillmer AM, Zang ZJ, Yao F, Jacques PE, Teo AS, Cutcutache I,...
View ArticleKruglyak paper on C. elegans
A paper on C. elegans that’s very informative: http://www.nature.com/ng/journal/v44/n3/full/ng.1050.html Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity Most notable of...
View ArticleFinding the lost treasures in exome sequencing data
Finding lost treasures in #exome sequencing data. Mining off-target, often noncoding, reads from 1000G, TCGA, ESP, &c http://www.ncbi.nlm.nih.gov/pubmed/23972387
View ArticlePLOS ONE: Burst of Young Retrogenes and Independent Retrogene Formation in...
Burst of Young Retrogenes…in Mammals. Discusses much retro-transposition ~40 Mya, relevant to proc. #pseudogenes http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0005040 Also, ref #11...
View ArticleInformation-theoretic evaluation of predicted ontological annotations
http://bioinformatics.oxfordjournals.org/content/29/13/i53.short
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